I. (Core Value: Unparalleled Diagnostic Capability

High-resolution, non-invasive “optical biopsy”

Traditionally, to make a clear diagnosis of many diseases, a biopsy was required, which involves taking a small piece of tissue and observing it under a microscope. This is an invasive operation.

OCT provides cross-sectional images similar to biopsies, but it is completely contactless and non-invasive. Doctors can directly observe the microstructure of the surface and subsurface layers of tissues inside the body without the need for cutting, significantly reducing risks and patient discomfort.



2. Real-time imaging, guiding treatment

OCT imaging is extremely fast and can provide images in real time. This enables doctors to immediately assess the condition of the tissue during surgery or interventional treatment, thereby making more accurate decisions.

For instance, during cardiovascular interventional surgery, doctors can view in real time the nature of the plaques within the blood vessels and the adhesion of stents.



Ii. (Main Application Fields and Specific Assistance）

The application of OCT has expanded from ophthalmology to multiple medical fields. Here are some of its most important applications:

Ophthalmology - the most mature and widely applied field

This is a prime example of the success story of OCT technology, which has completely transformed the diagnosis and treatment of retinal diseases.

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Diagnosis of macular diseases: Precise diagnosis and staging of age-related macular degeneration (AMD), macular edema, macular holes and other diseases is the gold standard.

Glaucoma management: By precisely measuring the thickness of the retinal nerve fiber layer (RNFL), early diagnosis of glaucoma and objective monitoring of disease progression can be achieved.

Diabetic retinopathy: Early detection of subtle changes and edema in the retina to guide treatment.

Impact on the industry: It has led ophthalmic diagnosis from subjective two-dimensional fundus photography to an era of objective and quantitative three-dimensional microstructure analysis.



2. Cardiology - A rapidly developing frontier field

Intravascular OCT (IV-OCT) enters the interior of blood vessels through slender catheters for imaging.

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Precise assessment of plaques: Clearly distinguish lipid plaques, fibrous plaques and calcified plaques, and identify easily ruptured “vulnerable plaques”, which is something that traditional angiography cannot achieve.

Optimizing stent implantation: During percutaneous coronary intervention (PCI), guiding doctors to select stents of appropriate size and accurately assessing whether the stents are fully adhered and sufficiently dilated after the operation significantly reduces the risk of restenosis and thrombosis after the operation.

Impact on the industry: It has advanced coronary intervention therapy from the era of “walking according to the route map” with angiography to the era of “navigating with a high-brightness map on” with precision.



3. Combination of oncology and endoscopy

Integrating the OCT probe into the endoscope enables deep scanning of suspicious areas simultaneously during endoscopic examinations of the digestive tract, respiratory tract, etc.

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Early cancer diagnosis: In the gastrointestinal tract, respiratory tract, bladder and other areas, distinguish benign lesions from early cancer, guide the biopsy location, and increase the positive rate of biopsy.

Determine the tumor boundary: Assist surgeons in determining the precise boundary of the tumor during surgery to ensure complete resection while preserving as much healthy tissue as possible.

Impact on the industry: It has enhanced the depth and accuracy of endoscopic examinations and promoted the screening and diagnosis capabilities for early-stage tumors.



4. Dermatology

Skin OCT is similar to ophthalmic OCT and can perform high-resolution imaging of the skin’s surface layer.

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Non-invasive diagnosis: It assists in the diagnosis of skin tumors such as basal cell carcinoma and melanoma, as well as inflammatory diseases like eczema and psoriasis.

Treatment monitoring: Non-invasive monitoring of the efficacy of drug treatment or laser treatment.

Impact on the industry: It has reduced the need for some diagnostic biopsies and provided new tools for the dynamic monitoring of skin diseases.



Iii. (Summary of the Overall Impact on the Healthcare Industry)

1. Enhance the level of diagnosis and treatment: Early diagnosis, precise staging and personalized treatment of diseases have been achieved.
   
   
2. Enhance patient experience: Through non-invasive or minimally invasive examinations, patients’ pain, risk of complications and recovery time are reduced.
   
   
3. Reduce medical costs: Although OCT devices themselves are expensive, they can lower overall medical expenses in the long run by avoiding unnecessary surgeries, optimizing the treatment process and reducing complications.
   
   
4. Promoting scientific research development: It provides powerful in vivo imaging tools for medical research, accelerating the development of new drugs and in-depth understanding of disease pathological mechanisms.
   
   
   

The first step: Demarcate the boundaries of the “safe” and the environment (regional boundary security)
OCT devices

should not be directly exposed to public networks. First, it is necessary to plan the security domain.

1. Network partition isolation
   
   Medical equipment dedicated network: OCT devices, PACS servers, image storage servers, etc. are classified into an independent VLAN and logically isolated from the office network and the Internet.
   
   Firewall policy: Deploy firewalls at the network boundary and strictly follow the “principle of least privilege”. Only specific and necessary ports and IP addresses are allowed for communication (for example, port 104 of the DICOM protocol, a specific port of the hospital information system). Any illegal external access is prohibited.
   
2. Physical Access Control
   
   The computer room where OCT equipment and core servers are placed should implement strict physical access control and video surveillance management to prevent unauthorized physical contact.
   
   Step 2: Build a sturdy box for the "safe" (secure computing environment)
   This is the core layer that protects the data itself.
   OCT Equipment and Terminal Security:
   Strengthen the operating system: Enhance the security of the operating system of the industrial control computer or computer built into the OCT device, as well as that of the diagnostic workstation.
   Anti-virus software: Install hospital-specific anti-virus software and update the virus database regularly.
   Identity authentication: It is mandatory to log in to the system with a unique personal username and a strong password. For the third-level information security protection, two-factor authentication should be mandatory.
   
3. Data storage encryption (lock of the safe) :
   
   Static data encryption: All OCT image data must be encrypted when stored on the disk. Available options:
   
   Transparent database encryption: Encrypting sensitive fields in the database.
   
   Storage layer encryption: Encrypt the entire disk or volume using the built-in encryption function of the storage device or operating system-level encryption.
   
   File-level encryption: Encrypting a single DICOM file.
   
   Key management: Encryption keys must be uniformly managed by a professional key management system, stored separately from encrypted data, and rotated regularly. This is the key point of the requirements for the equal protection.
   
4. Application Security
   
   Ensure that the PACS software and OCT device software themselves have no known high-risk vulnerabilities, and conduct regular security assessments.
   
   Step 3: Ensure "safety during transportation" (communication network security)
   When data is transmitted between OCT devices, PACS servers and diagnostic workstations, it is necessary to prevent eavesdropping and tampering.
   
5. Transmission encryption
   
   Enforce the use of encryption protocols such as DICOM over TLS or DICOM over HTTPS to replace the traditional plaintext DICOM protocol. This ensures that data is encrypted when transmitted over the network, similar to HTTPS protecting web page communication.
   
   For scenarios such as remote consultation that require cross-internet transmission, a VPN encrypted tunnel must be established.
   
   Step 4: Establish a monitoring and management center for the "safe deposit box" (Safety Management center)
   This is the brain and nerve center of the "safe", responsible for monitoring, auditing and emergency response.
   
6. Log audit (recording who opened the box) :
   
   Collect all logs related to OCT data centrally, including: user login/logout logs, logs of OCT image creation, modification, deletion, access, printing, export and other operations. These logs must be retained for no less than six months.
   
   The information security protection level requires that the content of logs cannot be tampered with, so it is necessary to deploy a professional log auditing system.
   
7. Database Audit
   
   For operations that directly access the database, a database auditing system is deployed to record all access behaviors to OCT data tables, especially high-risk operations.
   
8. Operation and Maintenance Management and Security Audit
   
   Video the operations of system administrators and record instructions to achieve traceability.
   
   Regularly conduct security risk assessments and vulnerability scans.
   
9. Data Backup and Recovery (Spare key for the safe) :
   
   Formulate a complete data backup strategy and regularly back up OCT image data and related patient information.
   
   Regularly conduct disaster recovery drills to ensure that business and data can be quickly restored in the event of data loss, system downtime or ransomware attacks. Backup data also needs to be encrypted for protection.
   

   
   

   
   

   Also welcome to contact us, we are ZD Medical Inc.
   Tel : +86-187 9586 9515
   Email : sales@zd-med.com
   Whatsapp/Mobile : +86-187 9586 9515

The International Day of the Blind on October 15th every year is a day that calls for attention to eye health and conveys the hope of light. When we focus on the living predicaments of the visually impaired group, a set of data should prompt more deep thought…

The silent threat of blindness: The insidious nature of retinal diseases

Retinal diseases such as diabetic retinopathy (DR) and age-related macular degeneration (AMD) have become the leading causes of irreversible blindness in China, and most patients have missed the best intervention opportunity by the time they show obvious symptoms. According to statistics, over 250 million people worldwide suffer from vision impairment, and nearly half of them can avoid it through early intervention. However, the limitations of traditional examination methods have caused many patients to miss the best treatment opportunity. In this race against darkness, ZD Medical  precise diagnosis and treatment solutions centered on optical coherence tomography (OCT) scanners are becoming a key force in preventing blindness.

I. Patient Comfort Experience

Comfort focuses on positive physical and psychological feelings, emphasizing “painless” and “relaxed”.

1- Contactless and pressure-free scanning process:

Experience: The device scans just a few centimeters above the skin without touching the body at all. Compared with the tight feeling of traditional tourniquets and the pressure sensation when nurses touch and search for blood vessels, this is a zero-invasive and zero-discomfort experience.

Value: Especially suitable for patients with sensitive skin, burns or trauma, it avoids the pain that may be caused by contact.

2- Painless and non-invasive imaging technology:

Experience: Vein Finder typically uses safe near-infrared light. The patient cannot see this kind of light and does not feel any stimulation at all, just like being illuminated by an ordinary flashlight. However, they can see the vascular images magically projected onto their skin.

Value: It eliminates the fear of technologies such as “radiation” and “laser”, and the process is very gentle.

3- Distract attention and relieve anxiety

Experience: For children and patients who are afraid of needles, seeing a clear image of the blood vessels on their arm is like an interesting “magic trick” or video game, which can effectively divert their attention from the upcoming puncture.

Value: Transforming a terrifying experience into a novel technological interaction significantly reduces psychological tension.

4- Shortened the anxiety time in the preparation stage:

Experience: Nurses no longer need to repeatedly touch and pat their arms for a long time to search for blood vessels. The “instant positioning” reduces the patient’s torment while waiting for puncture.

Value: The process is smooth and rapid, avoiding the prolonged anxiety caused by uncertainty.



Ii. Establishment of Patients’ sense of security

Security stems from a sense of “controllability” and “trust” in the process, emphasizing “reliability” and “peace of mind”.

1- The sense of control brought by visualization:

Experience: Patients can see the distribution of their subcutaneous blood vessels with their own eyes and understand the reasons why nurses choose puncture points. This “information transparency” endows patients with an unprecedented sense of participation and control.

Value: Transforming from a passive recipient to an active participant has greatly enhanced psychological security. “I can see it, so I’m relieved.” “

2- Expectations for high success rates:

Experience: The patient understands that the purpose of using high-tech equipment is to “hit the nail on the head”. This clear “expectation of success” directly offsets the fear of “repeated puncture failures”.

Value: Establishing a powerful psychological suggestion that “this operation will go smoothly” is the cornerstone of a sense of security.

3- Transfer of trust in the skills of medical staff:

Experience: Vein Finder is regarded as an authoritative auxiliary tool. The patient would think: “The hospital has introduced such advanced equipment, which shows that they attach great importance to and are committed to reducing my pain.”

Value: The equipment enhances patients’ trust in the professionalism of the entire medical team, and this sense of trust will translate into a sense of security.

4- Deep Reassurance for Special Groups

For parents of children: Seeing medical staff operate on their children in such a gentle and precise way brings great comfort.

For long-term patients (such as those undergoing chemotherapy) : Their blood vessels are fragile and in need of protection. Vein Finder can help select the best blood vessels and avoid damage. This “blood vessel protection” itself is a deep-seated commitment to safety.

I. Core Technological advantages: More efficient therapeutic effects

Ultrafine atomization for more efficient absorption:

Advantages: It breaks down the liquid medicine or artificial tears into extremely fine mist-like particles (usually with diameters ranging from 1 to 5 micrometers), which are much smaller than those of traditional eye drops. This enables the drug to cover the entire ocular surface more evenly and thoroughly, including the hard-to-reach meibomian gland openings and conjunctival fornix, significantly increasing the effective absorption area and bioavailability.

2. Deep nourishment, directly reaching the lesion

Advantages: The gentle and continuous mist can penetrate to the edge of the eyelid and directly act on the blocked meibomian glands, helping to soften blebum and improve the fundamental problem of “evaporative dry eye”. This is something that cannot be achieved simply by using eye drops.



Ii. User Experience Advantages: More comfortable and safe

1. Contactless treatment to avoid secondary injury:
   
   Advantage: During the treatment process, the eyeball does not need to come into contact with any instruments, greatly reducing the risk of infection that may result from contact (especially for patients with corneal damage or those who have undergone eye surgery). It also avoids the possible contamination of the medicine bottle mouth.
   
2. Gentle and comfortable, with an excellent experience:
   
   Advantages: Compared with the sudden impact and possible stinging sensation when the liquid drops in, nebulization therapy is a gentle, warm and continuous process. Users can receive treatment with their eyes naturally open or slightly closed in a relaxed state, without any foreign body sensation. It is especially suitable for children, the elderly or patients who are afraid of using eye drops.
   
3. Maintain the physiological state of the eyes without interfering with the tear film
   
   Advantage: Traditional eye drops wash away the normal tear film when applied, which may cause temporary blurred vision. Nebulization therapy is carried out in the form of “supplementation” and “moisturization”, without damaging the original structure of the tear film, and the visual quality is more stable after treatment.
   
   Iii. Functional and Scenario Advantages: More convenient and multi-functional
   
4. Multi-functional in one device, capable of both treatment and relief
   
   Advantages: In addition to using the special liquid prescribed by the doctor for treatment, users can also use sterile normal saline or special artificial tears for nebulization in daily life as a health care method for daily eye moisturization and relieving eye fatigue. It has achieved full coverage from “treatment” to “care”.
   
5. Family-oriented and portable, enhancing treatment compliance
   

   Advantage: With the popularization of portable home nebulizers, patients can bring professional-level care home. There is no need to frequently visit the hospital, which greatly facilitates patients with chronic dry eye syndrome who require long-term management, significantly improves treatment compliance, and thus ensures long-term therapeutic effects.

   
   

   Also welcome to contact us, we are ZD Medical Inc.
   Tel : +86-187 9586 9515
   Email : sales@zd-med.com
   Whatsapp/Mobile : +86-187 9586 9515

   
   

A clean, comfortable exam experience starts with the little details — and a high-quality Disposable Paper Bedsheet Roll makes a big difference. Clinics, spas, and mobile healthcare teams rely on disposable sheets to maintain hygiene between patients while keeping setup and cleanup quick. Designed for single-use convenience, these rolls help reduce cross-contamination risks and improve workflow in busy exam rooms.

For practitioners who need reliable, professional coverings, options such as Medical Couch Rolls and the Examination Couch Cover Roll are engineered to fit standard couches and trolleys, tear cleanly at perforations, and provide a soft, skin-friendly barrier. Good rolls balance strength and softness, resist minor fluids, and are available in a range of widths and ply to suit consultations, procedures, and physiotherapy sessions — all while being lightweight to store and simple to replace between patients.

At our factory we combine practical design with production discipline. With over 20 years’ experience manufacturing disposable medical disposables and supplying the global market, we offer OEM/ODM flexibility, consistent quality control, and competitive lead times. Customers benefit from tailored sizing, custom printing, and small-batch sampling so you can trial products before committing to larger runs. Our teams handle logistics and documentation for international shipping, making it straightforward to stock exam rooms anywhere in the world.

1.What is Platelet?

Platelets, fragments of cytoplasm derived from bone marrow megakaryocytes, play a central role in hemostasis and thrombosis. When blood vessels are injured, platelets adhere, activate, and aggregate to stop bleeding. Abnormal platelet function can lead to bleeding disorders or thrombotic events. With the widespread use of antiplatelet drugs, such as aspirin and clopidogrel, precise assessment of platelet activation function is increasingly important. Poclight’s next-generation Homogeneous CLIA (Chemiluminescence Immunoassay) technology brings a new level of accuracy and speed to platelet function testing.

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2.Platelet Function and Clinical Significance

Platelet-mediated hemostasis involves three key steps:

a. Adhesion

When the endothelium is disrupted, platelets adhere to the vessel wall via von Willebrand Factor (VWF) and collagen. This process is mediated by glycoprotein receptors CD42a/b/d (GPIb-IX-V), a critical step in platelet adhesion.

b. Activation

Platelets are activated through G-protein-coupled receptors binding to ligands such as thrombin, ADP, ATP, and prostanoids. Activated platelets change shape to a dendritic or octopus-like form.

c. Aggregation

Activated platelets are interconnected by fibrinogen and receptors CD41/61 (GPIIb/IIIa). Platelet granules release their contents into the extracellular fluid, among which CD62P (P-selectin) promotes platelet aggregation through platelet–platelet and platelet–fibrin interactions.

Platelet function

Hemostasis and thrombosis: The Key Role of Platelets 

Physiological function: The biological behavior and function of platelets are extremely complex. This includes participating in hemostasis and coagulation, maintaining vascular function, regulating inflammation, the body's immune defense, wound healing, tumor growth and metastasis, etc. Therefore, in clinical activities, the monitoring of platelet functionality is receiving increasing attention.

The average lifespan of platelets is 7 to 9 days. Senescent and dead platelets are eventually phagocytosed and processed in the spleen through the bloodstream.

Clinical Significance

1. Thrombosis Risk Assessment:  Patients with Hypertension, diabetes,coronary, artery disease,and other cardiovascular condition, as well as those on antiplatelet or anticoagulant therapy.
2. Pre/Postoperative Evaluation: Predicting thrombus formation and guiding prophylactic measures.
3. Platelet Dysfunction Disorders: For example, Glanzmann’s thrombasthenia (CD41/61 deficiency) and Bernard-Soulier syndrome (CD42a/b/d deficiency).
4.  Antiplatelet Therapy Monitoring: Supporting decisions for drugs like clopidogrel, ticagrelor, and prasugrel.
5. Various detection functions：

3. Advantages of Poclight Platelet Activation Function Test

Technical Highlights:

Employs Homogeneous CLIA technology to detect multiple platelet surface markers (CD41, CD42, CD61, CD62P) for comprehensive assessment.

Evaluates the full spectrum of platelet function—adhesion, activation, and aggregation—delivering more comprehensive and physiologically-relevant results.

4. Compatible Devices

The Poclight Platelet Activation Function Test is fully compatible with Poclight latest C5000 Analyzer, offering seamless integration into clinical and point-of-care settings. Key compatibility features include:

1. Plug-and-Play Operation: Simple one-step sample addition for immediate testing.
2. Portable Analyzer Integration: Works with compact, maintenance-free devices suitable for outpatient clinics or bedside monitoring.
3. Future Expansion: Designed to support upcoming analyzer models based on the Homogeneous CLIA platform.
4. Note: For detailed technical specifications and compatibility with your laboratory instruments, please contact our technical support team at overseas@poclight.com.

5. Clinical Applications

1. Outpatient Thrombosis Risk Screening: Quickly assess high-risk patients and guide antiplatelet therapy.
2. Pre/Postoperative Monitoring: Track platelet activity changes to optimize surgical management.
3. Antiplatelet Drug Efficacy Evaluation: Support individualized medication decisions and reduce bleeding or thrombotic events.
4. Diagnosis of Platelet Dysfunction Disorders: Provide molecular-level insights for rare platelet diseases.

6.Influencing factors

1. Genetic factors: Genes determine each person's basic platelet activity and their response to drugs.
2. Drugs: Antiplatelet drugs, NSAIDs (such as ibuprofen), certain antibiotics, antidepressants, etc., can all affect their function.
3. Disease status: Chronic diseases such as diabetes, kidney disease, and autoimmune diseases are often accompanied by high platelet reactivity (easier to form blood clots).
4. Lifestyle:

Diet: Omega-3 fatty acids, garlic, ginger, certain vitamins (such as VC, VE) may inhibit platelet function.

Smoking and drinking: Smoking activates platelets, while moderate drinking may inhibit them.

Physiological conditions: Stress, exercise, and aging can all increase platelet activity.

7.Future Outlook

Platelet activation function testing is evolving towards speed, portability, standardization, and intelligence. Poclight’s Homogeneous CLIA platform not only shortens testing time but also delivers reliable, high-quality data, supporting precise assessment of bleeding and thrombotic risk. With ongoing technological innovation, this approach will play an increasingly vital role in precision medicine and individualized patient care.

8.Chemiluminescence resonance energy transfer（CRET）

Detection principle:

CRET cell technique utilizes the molecules on the platelet membrane to specifically fix and bind to the corresponding antibody 1-labeled DNA1, antibody 2-labeled DNA2, and AE-labeled DNA3 to form complexes. By detecting the light intensity via CRET, the expression levels of various antigens and receptor molecules in the sample can be detected.

Detection method:

1. Nucleic acid technology is integrated into immunodiagnosis, leveraging the proximity efffect of nucleic acids takes effect.
2. The properties of graphene oxide are strategically utilized, eliminating the need for magnetic beads and their associated separation and washing steps, and simplifying the fluidic path.
3. The introduction of enzymatic cycling amplification technology enhances detection sensitivity by 1 to2 orders of magnitude, improving overall performance while simultaneously simplifying the process.

Advantage:

CRET compensates for the drawbacks of flow cytometry and enables:

1. Fast, reliable detection in just 5-10 minutes.
2.  A simple and minimalist operational procedure.
3. Low-cost testing with no hidden fees.
4. Easy adoption in all levels of hospitals and departments.
5. Accurate in vivo status: Not affected by platelet aggregation or in vitro activation issues. 

Contact Us

E-mail: overseas@poclight.com

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