{ Point-of-Care Testing (POCT) analyzer }

  • Test Sooner, Act Faster – Enhance Sepsis Care with Poclight Diagnostics

    |

    1. The Global Burden of Sepsis

     

    Sepsis is a life-threatening condition caused by the body’s extreme response to infection.

    From data published in 2020, globally, over 49 million people are affected each year, with approximately 11 million deaths, representing 20% of all global deaths (Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Lancet. 2020 Jan 18).

     

    sepsis worldwide

     

    Sepsis affects people globally, but incidence and mortality are highest in lower-middle-income countries (LMICs). In high-income countries, the average hospital cost per sepsis patient exceeds US$32,000.

     

    Understanding the Risk

    Anyone can develop an infection that leads to sepsis, but certain factors increase susceptibility. Older adults, infants (40% of all cases), pregnant women, and patients with pre-existing conditions—such as chronic kidney disease, liver disease, cancer, or heart failure—face higher risk.

     

    sepsis in children

    early diagnosis of sepsis

     

    Socioeconomic factors, access to healthcare, and living conditions also play a role, particularly in low- and middle-income countries where infections may be more prevalent and timely medical care is harder to access.

    ● High-risk populations: older adults, infants (half of all cases), pregnant women

    ● Pre-existing conditions: chronic kidney disease, liver disease, cancer, heart failure

    ● Socioeconomic & environmental factors: limited healthcare access, overcrowded living, poor sanitation

     

    2. The Role of Biomarkers in Sepsis Diagnosis

     

    Inflammatory biomarkers are measurable indicators of the body’s immune response to infection. In sepsis, key inflammatory biomarkers may include the following:

    sepsis biomarkers

    Sepsis, septic shock, and sepsis-associated encephalopathy biomarkers. (Barichello, T., Generoso, J.S., Singer, M. et al. Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review. Crit Care 26, 14 (2022))

     

    kinetics of key inflammation markers

    Biomarker Kinetics After Bacterial Infection

     

    Clinical benefits of monitoring these biomarkers:

    ● Early detection of sepsis and assessment of severity

    ● Informed decisions on initiating, adjusting, or discontinuing antimicrobial therapy

    ● Support antimicrobial stewardship (AMS): Reduced unnecessary antibiotic exposure without increasing mortality

    ● Real-time monitoring of treatment effectiveness alongside pathogen identification and antibiotic susceptibility testing

     

    3. Poclight’s Solution: Speed, Precision, and Accessibility

     

    Poclight’s C5000 dry chemiluminescence immunoassay system offers a reliable approach to testing a panel of inflammatory and sepsis-related biomarkers, including PCT, CRP, IL-6, and HBP.

    Category

    Test

    Sample types

    Assay duration

    Sample volume

    Cut-Off value of Sepsis

    Measuring range

    INFLAMMATION

    CRP test kit

    Serum/Plasma

    /Whole Blood

    3min

    5 μL

    >100 mg/L

    >10 mg/L neonatal

    (low specificity, cannot diagnose sepsis alone)

    0.5~320 mg/L

    IL-6 test kit

    Serum/Plasma

    15min

    100 μL

    >250 pg/mL possible sepsis

    1.5~5000 pg/mL

    PCT test kit

    Serum/Plasma

    5min

    200 μL

    >0.5 ng/mL

    high risk of sepsis

    0.02~100 ng/mL

    HBP test kit

    Plasma

    5min

    50 μL

    >28.1 ng/mL

    5.9~300 ng/mL

    Note: The reference values provided for each biomarker are for guidance only. Final clinical diagnosis should not rely on a single parameter, but instead be based on a comprehensive assessment that combines multiple biomarkers, diagnostic tools, and clinical evaluation.

     

    1)  High Sensitivity & Specificity

    Fully homogeneous chemiluminescence technology enables precise detection of small-molecule hormones and inflammatory markers, minimizing false results.

    2)  Single-Test Freeze-Dried Reagents

    Each assay comes as a single-dose, freeze-dried reagent that is stable at room temperature for up to 18 months, simplifying storage and transport—ideal for hospitals, primary care clinics, and remote settings.

    Poclight freeze-dried reagents

     

    3)  Rapid Turnaround

    Test results in as fast as 3 minutes, enabling fast clinical decisions in critical situations.

    4)  Cost-Effective: Low per-test cost allows frequent testing, saving healthcare budgets.

    5)  Versatile and User-Friendly

    Compact, simplified instruments make the system suitable for diverse clinical environments, from GP, clinics, to labs.

    C5000 analyzer

     

    By enabling early and accurate sepsis detection, Poclight diagnostics support clinicians in providing timely treatment while avoiding unnecessary broad-spectrum antibiotic use.

     

    Detect sepsis early, respond rapidly, and save lives - Care in Time with Poclight

    Get in touch with our specialists to get started and discover how we can help.

  • Upgrade Your IL-6 Testing Workflow with Poclight’s Fast & Reliable POC CLIA Solution

    |
    1.  Introduction

    Inflammation is a key response of the body to infection, tissue injury, or other stressors. Early detection is critical because timely recognition can guide treatment decisions and improve patient outcomes.

    Interleukin-6 (IL-6) is a pro-inflammatory cytokine released by immune cells in response to infection or tissue damage. Its levels rise within 2 hours, significantly earlier than PCT (>2 hours) and CRP (>6 hours). This rapid increase makes IL-6 a valuable marker for early detection of systemic inflammation across a variety of clinical scenarios.

    Inflammation marker kinetics

    Figure: Kinetics of Key Inflammatory Markers After Bacterial Infection

     

    2.  Practical Value of IL-6 Testing

    In clinical practice, IL-6 is used across multiple scenarios:

    ● Hospitals and clinics: Early detection of sepsis and other acute inflammatory conditions.

    ● Laboratories: Rapid and reliable measurement of IL-6 supports timely reporting and monitoring.

    ● Specialized departments: Post-surgical care, transplant units, pulmonary wards, and oncology can use IL-6 to assess infection, tissue injury, immune response, or tumor progression.

     

    3.  Core Advantages of Poclight IL-6 Test Kit

     

    (1)  High Sensitivity & Wide Range

    ● Detects IL-6 down to 1.5 pg/mL with a range of 1.5–5000 pg/mL, covering early-stage inflammation to severe conditions.

     

    (2)  Small Sample Volume & Rapid Results

    ● Only 100 μL of serum or plasma needed, with 15-minute turnaround, ideal for fast clinical decisions.

     

    (3)  Room-Temperature Lyophilized Reagents

    ● Freeze-dried reagents require no cold chain and have a shelf life of 18 months, simplifying storage and transport.

     

    (4)  Easy-to-Use:

    ● Applicable with the C5000 POC CLIA Analyzer: 3-Step Operation, Maintenance-Free Design

    Easy 3-step operation

    ● QR code-based standard curve calibration

    ● Minimal upkeep make operation simple and reliable

     

    3.1 Assay Specification

    IL-6 Reagent Box

     

    Item

    Specification / Value

    Detection Limit (LOD)

    1.5 pg/mL

    Measurement Range

    1.5~5000 pg/mL

    Sample Volume

    100 μL

    Sample Type

    Serum / Plasma

    Assay Time / Turnaround

    15 min

    Precision (CV%)

    <5%

    Cut-off value

    ≤7 pg/mL normal

     

    3.2 Results Interpretation

     

    IL-6 Level (pg/mL)

    Clinical Interpretation

    < 7

    Normal

    7–150

    Indicates mild inflammation or mild infection

    150–250

    Suggests general bacterial infection or systemic inflammatory response

    > 250

    Strongly suggests sepsis or severe systemic inflammation

     

    Ready for fast, accurate POC IL-6 testing?

    Contact us today and experience how Poclight can upgrade your workflow!

     

  • Elevate Your Diagnostic Capabilities with MINI Automatic Chemiluminescence Immunoassay Analyzer

    |

    In a fast-evolving healthcare landscape, laboratories and medical professionals are seeking reliable, affordable, and high-performance solutions for diagnostic testing. At Poclight Biotech, we deliver on all fronts—combining innovation, affordability, and global cooperation to bring next-generation testing systems like the Mini-CLIA Chemiluminescence Analyzer to the forefront of point-of-care and laboratory diagnostics.

     

    Whether you’re looking for a Inflammation Rapid Test, Cardiac Test Kit, Thyroid Test kit, Tumor Marker test analyzer, Hormones Fertility Rapid Test, Diabetes Test kits, Bone Metabolism Test, Anemia Test, Allergy Preeclampsia Test, or a cutting-edge CLIA analyzer, Poclight offers products that consistently meet international quality standards—at competitive prices.

     

    Mini-CLIA: Small in Size, Big in Performance

    Our Mini-CLIA Chemiluminescence Immunoassay System is a compact yet powerful bench-top analyzer designed to integrate advanced CLIA technology with the flexibility and speed of POCT (Point-of-Care Testing) systems.

    The analyzer utilizes the latest technology with exclusive intellectual property rights——CRET Technology to quantify or qualify target analytes in serum, plasma, whole blood. Powered by a PMT (photomultiplier tube), the system detects light signals, converts them into digital data, and processes results using a preloaded master calibration curve—ensuring high precision and accurate concentrations in every test.

     

    Key Features at a Glance

    • High sensitivity and specificity thanks to CRET chemiluminescence technology
    • The report can be generated in as little as 3 minutes
    • Only 3 steps: place the sample, wait, and get the report
    • LIS connectivity for seamless data exchange with hospital or laboratory information systems

     

    Mini Clia - China Manufacturers, Suppliers, Factory

     

    Why Choose Poclight?

    At Poclight, we’re more than just a manufacturer—we’re your long-term diagnostic partner. Here's what sets us apart:

     

  • Micro-sampling System Poclight

    |

    In today’s fast-paced healthcare environment, laboratories need reliable and efficient solutions for rapid diagnostics. Poclight is proud to introduce our latest micro-sampling solution, designed to meet the demands of precision and speed while addressing the complexities of sample handling. With its unique features, our product is set to revolutionize your testing capabilities.

     

    One of the standout attributes of our micro-sampling solution is its precise control over sample volume, requiring only 10μL for testing. This ensures that laboratories can minimize waste while maximizing accuracy, a crucial factor in environments where sample volume is critical. Additionally, the system allows for no washing or separation, streamlining the workflow and reducing the time spent on sample preparation.

     

    Efficiency is further enhanced with an operation time of just 2 seconds per sample. This rapid processing capability makes it ideal for high-throughput settings, such as emergency departments and large-scale screenings. Healthcare providers can expect quicker turnaround times, which is essential for timely diagnoses and treatment decisions.

     

    Micro-sampling solution is also designed for practical use. Poclight's clia test reagents can be stored at room temperature, eliminating the need for cold chain transport and allowing for long shelf life. This feature not only simplifies logistics but also ensures that the product is ready to use whenever needed, without the constraints of refrigeration.

     

    Poclight's poct clia analyzer are designed for minimal maintenance, with easy installation and user-friendly, one-step operation. This means your staff can focus on what matters most—providing quality care—without the hassle of complex setups or ongoing repairs.

     

    Advanced POCT CLIA Analyzer for Clinics and Labs

     

    Experience the advantages of our product today and elevate your laboratory’s diagnostic capabilities.

     

  • A Guide to Choosing the Right CLIA Kit

    |

    Chemiluminescent immunoassay (CLIA) kits have become indispensable tools in modern clinical laboratories, thanks to their high sensitivity, specificity, and automation potential. Whether you're screening for infectious diseases or monitoring tumor markers, understanding how these kits work and how to choose the right one is critical for reliable results and efficient diagnostics.

    1. Overview of Chemiluminescent Immunoassay Kits

    Chemiluminescent immunoassay kits detect specific antigens or antibodies based on a luminescent chemical reaction. Here’s how it works: an antigen-antibody binding event is coupled with a chemiluminescent substrate that emits light when catalyzed by an enzyme. The emitted light is then measured using a luminometer, with the intensity proportional to the concentration of the target analyte.

    Application Areas:

    - **Clinical Diagnostics**: thyroid function tests, cardiac markers.

    - **Infectious Disease Testing**: CRP, SAA, IL-6, PCT, KL-6, HBP, COVID-19 antibody/antigen detection.

    - **Tumor Marker Detection**: PSA, AFP, CA125, and more.

    - **Cardiac**: D-dimer, BNP, NT-proBNP, CK-MB, Myo, hs-cTnT, RF detection.

    - *Fertility Tests*: beta-hCG, Prolactin, Prog, Cortisol, FSH, AMH, Testosterone, LH, Estradiol

    Immunoassay Test-Kits

    2. Selection Criteria and Considerations

    ### Sensitivity and Specificity:

    The reliability of diagnostic results hinges on sensitivity (true positive rate) and specificity (true negative rate). High sensitivity ensures even trace amounts of biomarkers are detected, while high specificity reduces false positives. Always check:

    - Sensitivity % (ideally >95%)

    - Specificity % (ideally >95%)

    ### Detection Range:

    Different kits are tailored for specific analytes. Make sure to align your selection with your lab’s testing focus:

    - **Hormones**: TSH, LH, hCG

    - **Viral Markers**: HBsAg, HCV Ab

    Verify that the kit covers the necessary linear detection range for your sample type and concentration needs.

    3. Product Quality and Certification

    Quality assurance is non-negotiable in clinical diagnostics. Look for kits that carry:

    - CE Mark (Europe)

    - FDA Approval or EUA (U.S.)

    - ISO 13485 certification for manufacturing processes

    Additionally, consider the manufacturer's:

    - **Reputation**: Years in the market, reviews, known partnerships

    - **Production Standards**: GMP compliance, QC systems

    - **Batch-to-batch consistency**: Crucial for longitudinal studies or repeated testing

    4. Ease of Use

    Modern CLIA kits are often designed with automation in mind, but workflow simplicity still varies. Evaluate:

    - **Number of steps**: Manual vs. automated workflow

    - **Sample preparation**: Plasma, serum, whole blood compatibility

    - **Training Requirements**: Is the kit suitable for labs with limited technical personnel?

    A good kit should offer intuitive instructions and come with technical support when needed.

     5. Cost and Value for Money

    CLIA kits vary in price depending on:

    - Target analyte

    - Brand reputation

    - Certification level

    While budget is important, avoid choosing solely based on price. Instead, assess:

    - Cost per test

    - Shelf life and storage conditions

    - Bundled services or equipment availability

    One of Poclight's strongest advantages is that our analyzer offer a simple one-step operation, making it highly user-friendly. Additionally, our kits eliminate the need for washing or separation processes, which not only saves time but also reduces the potential for errors. With minimal maintenance requirements, these kits are designed to facilitate smooth workflows, ensuring that even labs with limited technical personnel can operate them effectively.

     

    Another strong advantage is the reagents is Lyophilized Beads NO COLD CHAIN NEEDED, NO refrigerators needed, with long shelf-life.

    This guide provides a comprehensive overview to help you choose the right chemiluminescent immunoassay kits for your laboratory needs.

  • Exciting Announcement Join Us at Hospitalar 2025 in Brazil!

    |

    We are thrilled to announce that Poclight will be showcasing our innovative instruments and reagents at the Hospitalar 2025 Medical Equipment Exhibition in Brazil this May. We invite both new and returning customers to visit our booth for an exclusive look at our cutting-edge products.

     

    Our featured testing kit utilizes the unique properties of graphene oxide, eliminating the need for magnetic beads and simplifying the process by removing complex separation and washing steps. This results in a more efficient workflow and enhances the overall performance of the assay.

     

    One of the standout benefits of Poclight's technology is the significant increase in sensitivity—by one to two orders of magnitude—allowing for more accurate and reliable results. This streamlined process not only improves performance but also makes it easier for healthcare professionals to obtain critical data.

     

    Additionally, our kits offers exceptional cost-effectiveness. With low testing costs, individual packing Lyophilized Beads reagents that don’t require refrigeration, we greatly reduce the risks associated with transportation and storage. The compact and user-friendly design of our instruments ensures versatility across various application scenarios.

     

    Don’t miss this opportunity to explore Poclight's innovative solutions and discuss how we can support your needs. We look forward to welcoming you at Hospitalar 2025!