Inflammation is a key response of the body to infection, tissue injury, or other stressors. Early detection is critical because timely recognition can guide treatment decisions and improve patient outcomes.

Interleukin-6 (IL-6) is a pro-inflammatory cytokine released by immune cells in response to infection or tissue damage. Its levels rise within 2 hours, significantly earlier than PCT (>2 hours) and CRP (>6 hours). This rapid increase makes IL-6 a valuable marker for early detection of systemic inflammation across a variety of clinical scenarios.

Figure: Kinetics of Key Inflammatory Markers After Bacterial Infection

 

2.  Practical Value of IL-6 Testing

In clinical practice, IL-6 is used across multiple scenarios:

● Hospitals and clinics: Early detection of sepsis and other acute inflammatory conditions.

● Laboratories: Rapid and reliable measurement of IL-6 supports timely reporting and monitoring.

● Specialized departments: Post-surgical care, transplant units, pulmonary wards, and oncology can use IL-6 to assess infection, tissue injury, immune response, or tumor progression.

 

3.  Core Advantages of Poclight IL-6 Test Kit

 

(1)  High Sensitivity & Wide Range

● Detects IL-6 down to 1.5 pg/mL with a range of 1.5–5000 pg/mL, covering early-stage inflammation to severe conditions.

 

(2)  Small Sample Volume & Rapid Results

● Only 100 μL of serum or plasma needed, with 15-minute turnaround, ideal for fast clinical decisions.

 

(3)  Room-Temperature Lyophilized Reagents

● Freeze-dried reagents require no cold chain and have a shelf life of 18 months, simplifying storage and transport.

 

(4)  Easy-to-Use:

● Applicable with the C5000 POC CLIA Analyzer: 3-Step Operation, Maintenance-Free Design

● QR code-based standard curve calibration

● Minimal upkeep make operation simple and reliable

 

3.1 Assay Specification

 

Item	Specification / Value
Detection Limit (LOD)	1.5 pg/mL
Measurement Range	1.5~5000 pg/mL
Sample Volume	100 μL
Sample Type	Serum / Plasma
Assay Time / Turnaround	15 min
Precision (CV%)	<5%
Cut-off value	≤7 pg/mL normal

 

3.2 Results Interpretation

 

IL-6 Level (pg/mL)	Clinical Interpretation
< 7	Normal
7–150	Indicates mild inflammation or mild infection
150–250	Suggests general bacterial infection or systemic inflammatory response
> 250	Strongly suggests sepsis or severe systemic inflammation

 

Ready for fast, accurate POC IL-6 testing?

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