The International Society on Thrombosis and Haemostasis (ISTH) established World Thrombosis Day (WTD) on October 13 to raise awareness of the global health threat.

Every year, 1 in 4 people worldwide die from conditions related to thrombosis, the underlying cause of the top three cardiovascular killers: heart attack, stroke, and venous thromboembolism (VTE). - World Thrombosis Day website (2025)

 

According to WHO data (2001–2023), the global age-standardized mortality rate of pulmonary embolism fell from 3.49 to 2.42 per 100,000. However, rates are rising in some lower-middle-income regions, underscoring the need to strengthen diagnostic capacity. Rapid and accessible POC testing helps bridge this gap where laboratory resources are limited.

 

2.  D-Dimer Testing Essentials

 

D-dimer is a specific fibrinolysis marker and key laboratory indicator of thrombus formation and breakdown. It rises within 2 hours of clot formation, has a 7-8 hour half-life, and remains stable in blood samples for 24-48 hours. These characteristics ensure its crucial role in diagnosing and monitoring thrombotic diseases.

Its clinical applications may include the following:

● Early Detection of Thrombosis: D-dimer testing is widely used to help rule out venous thromboembolism (VTE) in patients with suspected thrombotic events, particularly when combined with clinical assessment. Rapid detection supports prompt management decisions.

● Guiding Further Assessment: Prompts additional imaging or diagnostic tests.

● Supporting Anticoagulation Decisions: Helps guide initiation, adjustment, or duration of anticoagulant therapy.

 

Test Combination

 

Item	Clinical Use / Recommendation
D-dimer Test Kit	Helps rule out suspected DVT or PE (when combined with clinical probability assessment)
D-dimer + NT-proBNP Test Kit	Assists in differentiating PE from heart failure in patients with acute dyspnea
D-dimer + NT-proBNP and/or Troponin I	Helps rule out PE and assess PE prognosis

Note: D-Dimer levels can rise due to infection, inflammation, surgery, or pregnancy. It should always be interpreted alongside clinical findings and imaging.

 

3.  Poclight D-Dimer Solutions

 

Highly cost-effective, Poclight Biotech’s point-of-care D-dimer Test Kit solutions deliver results within 5 minutes, supporting prompt assessment and care.

 

Our Stand-out features:

 

1)  Small Sample Volume & Rapid Results

Only 50 μL of serum or plasma needed, with 5-minute turnaround, ideal for fast clinical decisions.

Parameter	Sample type	Assay duration	Sample volume	Cut-Off value	Measuring range
D-dimer	Plasma	5min	50 μL	0.5 mg/L, Higher D-dimer levels suggest clotting activity	0.25~20 mg/L

 

2)  Freeze-dried reagents: no cold chain, 18 months shelf life, simplifying storage and transport.

3)  High accuracy and excellent precision (CV < 5%)

 

 

4)  Applicable with the C5000 POC CLIA Analyzer: 3-Step Operation, Maintenance-Free

 

Contact us to learn about local distributors and pricing options for Poclight D-dimer solutions.